Here are the Boston Red Sox 2010 MLB Draft Picks for rounds 4-15. We’ll be back after round 30 with rounds 16-30.
| Pick (Rd) | Name | School | POS | B/T | Class |
| 143 (4th) | Garin Cecchini | Barbe HS (LA) | SS | L/R | HS |
| 173 (5th) | Henry Ramos | Alfonso Casta Martinez HS (PR) | RF | S/R | HS |
| 203 (6th) | Kendrick Perkins | La Porte HS (TX) | CF | L/R | HS |
| 233 (7th) | Chris Hernandez | Miami (FL) | P | L/L | JR |
| 263 (8th) | Mathew Price |
Virginia Tech | P | R/R | JR |
| 293 (9th) | Tyler Barnette | Hickory HS (NC) | P | R/R | HS |
| 323 (10th) | Jacob Dahlstrand | Memorial HS (TX) | P | R/R | HS |
| 353 (11th) | Lucas LeBlanc | Delgado College | OF | R/R | J2 |
| 383 (12th) | Garrett Rau | California Baptist Univ. | P | R/R | JR |
| 413 (13th) | Keith Couch | Adelphi Univ. | P | L/R | JR |
| 443 (14th) | Michael Hollenback | Joliet Township HS (IL) | C | L/R | HS |
| 473 (15th) | Stephen Wilkerson | Pope HS (GA) | SS | S/R | HS |
