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The sildenafil timeline, if any, of persistent and/or serious retinal changes with long-term sildenafil use or with use in older patients remains to be elucidated but the possibility should be considered. Sildenafil timeline current evidence suggests that the retinotoxic risk of sildenafil probably is low when used as recommended in otherwise healthy adults, some clinicians suggest that retinal function be monitored periodically in patients receiving the drug.

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