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Sildenafil
Clinical data
Pronunciation/ s ɪ l ˈ d ɛ n ə f ɪ l / sil- DEN -ə-fil
Trade namesViagra, Revatio, others
AHFS/Drugs.comMonograph
MedlinePlusa699015
License dataEU  EMA:  by INN, US   FDA: Sildenafil
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationBy mouth (tablets), IV
ATC codeG04BE03 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: P (Pharmacy medicines) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability41% (mean) [1]
Protein binding~96%
MetabolismLiver: CYP3A4 (major route), CYP2C9 (minor route)
MetabolitesN -desmethylsildenafil (~50% potency for PDE 5 )
Elimination half-life3–4 hours
ExcretionFeces (~80%), urine (~13%) [2]

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Viagra contraindications for use REVATIO is viagra contraindications for use to treat arare disease called pulmonary arterial hypertension PAH VIAGRA should not be used with REVATIO or with other PAHtreatments containing sildenafil or any other PDE5 inhibitor such as Adcircatadalafil VIAGRA does not protect against sexually viagra contraindications for use diseases, including HIV. The most common side effects of VIAGRA: headache; flushing; upset stomach; abnormal vision, such as changes in color visio such as having a blue color tinge and blurred vision; stuffy or runny nose; back pain; muscle pain; nausea; dizziness; rash.

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In some patients, the useof VIAGRA with alpha-blockers can lead to a drop in blood pressure or to fainting medicines called HIV protease inhibitors, such as ritonavir Norvir indinavir sulfate Crixivan saquinavir Fortovase or Invirase or atazanavir sulfate Reyataz some types of oral antifungal medicines, such asketoconazole Nizoral and itraconazole Sporanox some types of antibiotics, such as clarithromycin Biaxin telithromycin Ketek or erythromycin VIAGRA contains sildenafil, which is the same medicine foundin another drug called REVATIO.

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Surgery or penile implants may be an option for severe cases. Symptoms of Peyronie's disease include pain during intercourse or ejaculation, erectile dysfunction ED, impotence the inability to have sexual intercourse, anxiety, stress, an indentation of the shaft at the site where there is plaque or scarring, and an angulation of the penis when erect or flaccid. viagra contraindications for use

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The products discussed in this site may have different product labeling in different countries. The product information provided in this site is intended only for residents of the United States. ov/MedWatch or call 1-800-FDA-1088.

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