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Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Viagra sildenafil how much viagra cost around the same times every day, and space your doses about 4 to 6 hours apart.

Because of the potential cardiovascular effects of sildenafil and the lack of safety information on use of the drug in patients with severe or unstable heart disease, the drug should be used with caution in patients with active coronary ischemia who are not receiving nitrates or nitrites, with congestive heart failure and borderline low blood pressure or low blood volume, with left-ventricular outflow obstruction, with diseases impaired hepatic or renal function that may alter the excretion of sildenafil, and in those receiving a complex multidrug antihypertensive regimen or drugs e.

heart failure, coronary artery how much is the generic viagra, unstable angina No clinical trial data are available on the safety and efficacy of sildenafil in patients with PAH and coexisting recent within 6 months myocardial infarction, stroke, or life-threatening arrhythmia; coronary artery disease causing unstable angina; or hypertension blood pressure exceeding 170/110 mmHg If sildenafil is used for the treatment of PAH in such patients, caution is advised.

METS in cardiovascular responses for male-on-top coitus was observed, and thus simply equating a level of cardiac or metabolic expenditure during sexual intercourse to activity such as climbing 1 or 2 flights of stairs may underestimate the how much is the generic viagra cardiovascular response. Most clinical trials with sildenafil for the treatment of ED excluded patients with recent less than 6 months myocardial infarction, stroke, life-threatening arrhythmia, or uncontrolled hypertension blood pressure exceeding 170/110 mm Hg and how much is the generic viagra a small fraction of the patients studied had heart disease e.

erythromycin, cimetidine that may alter the elimination of sildenafil. Patients with PAH should inform their clinician of coexisting chest pain or recent within 6 months myocardial infarction, stroke, or arrhythmias prior to initiation of sildenafil.

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Sildenafil clearance is reduced in geriatric adults 65 years of age and older and in adults with severe renal or hepatic impairment. Free unbound plasma drug concentrations in healthy geriatric adults are approximately 45% greater than those in healthy younger adults 18-45 years Such age-related reductions how much is the generic viagra clearance of the drug do not appear to be attributable to age-related declines in creatinine clearance but result from age-related differences in plasma protein binding.

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In patients with mild creatinine clearance ranging from 50-80 mL/minute or moderate creatinine clearance ranging from 30-49 mL/minute renal impairment, the pharmacokinetics of a single 50-mg oral dose of sildenafil are not altered. However, in patients with severe how much is the generic viagra clearance less than 30 mL/minute renal impairment, sildenafil clearance is reduced, resulting in AUCs and peak plasma concentrations of the parent drug that are approximately double those in age-matched healthy adults.

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These generic drugs and Viagra are bioequivalent, which means they act the same way and produce the same results in the body. These medicines are also approved by the FDA to treat erectile dysfunction. It's important how much is the viagra pill note that, like the effects of Viagra, the effects of these generic medications don't include spontaneous erection. Generic Viagra is another term for medicine with the active ingredient and dosage as Viagra, but it is not sold under the brand name.

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