It has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber. Methocarbamol (robaxin) box 500 mg 120 amount in a package.
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NA: Information not available. Risks is this a narcotic methocarbamol outweigh potential benefits. Unknown; possibly general CNS depression induces skeletal muscle relaxation Onset: 30 min Peak serum time: 1-2 hr Peak plasma concentration: 16. -29. mcg/mL Protein binding: 46-50% Liver dealkylation and hydroxylation Metabolites: Glucuronide and sulfate conjugates of 3 2-hydroxyphenoxy 1, -propanediol-1-carbamate and 3 4-hydroxy-2-methoxyphenoxy 1, -propanediol-1-carbamate; unidentified metabolites Half-life: 0.
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- In dogs, methocarbamol is widely distributed, with highest concentrations attained in the kidney and liver; lower concentrations are attained in the lungs, brain, and spleen, and is methocarbamol a narcotic concentrations are attained is methocarbamol a narcotic heart and skeletal muscle. Data from the unpublished study also indicate that after IV administration of 1 g of methocarbamol at a rate of 300 mg/minute, blood concentrations of 19 mcg/mL are attained immediately and that the onset of action is almost immediate.
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In horses it may be prescribed for sore backs, muscle strains, exertional rhabdomyolysis. It may be prescribed in dogs and cats in conditions such as intervertebral disc disease and traumatic muscle strains. It may be prescribed in dogs and cats is this a narcotic methocarbamol conditions such as intervertebral disc disease and traumatic muscle strains.
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