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Hemodynamics: Following administration of therapeutic doses to patients with hypertension, Amlodipine produces vasodilation resulting in a reduction of lotrel amlodipine and standing blood pressures. Amlodipine is a peripheral arterial vasodilator that acts directly on vascular smoothmuscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure. Vasospastic Angina: Amlodipine has been demonstrated to block constriction and restore blood flow in coronary arteries and arterioles in response to lotrel amlodipine, potassium epinephrine, serotonin, and thromboxane Lotrel amlodipine analog in experimental animal models and in human coronary lotrel amlodipine in vitro.

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