Taking this medication during pregnancy can cause birth defects and may lower your child's IQ. Women of childbearing age should discuss the risks and benefits of this medication, other treatment options, and use of reliable forms of birth control with their doctor. Depakote (divalproex) packaging 125 mg 120 quantity in a package.
Most children do best at about 15 to 60 mg/kg per day. Children taking a combination of Depakote and another seizure medicine usually need the depakote and weight gain causes doses because of interactions between the medicines. They can switch to Depakote ER when they reach a higher dosage.
Other birth defects that affect the structures of the heart, head, arms, legs, and the opening where the urine comes out urethra on the bottom of the penis can also happen.
These defects can begin in the first month, even before why does depakote cause weight gain know you are pregnant. If you take DEPAKOTE during pregnancy for any medical condition, your baby is at risk for serious birth defects that affect the brain and spinal cord and are called spina bifida or neural tube defects.
These defects occur in 1 to 2 out of every 100 babies born to mothers who use this medicine during pregnancy.
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Why does depakote cause weight gain
Talk to your healthcare provider about the best way to feed your baby if you take Depakote or Why does depakote cause weight gain. Before you take Depakote or Depakene, tell your healthcare provider if you: have a genetic liver problem caused by a mitochondrial disorder e.
Alpers-Huttenlocher syndrome are pregnant or breastfeeding. have or have had depression, mood problems, or suicidal thoughts or behavior Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, herbal supplements and medicines that you take for a short period of time. Why does depakote cause weight gain Depakote or Depakene with certain other medicines can cause side effects or affect how well they work.
Depakote or Depakene can pass into breast milk.
Use of valproic acid during pregnancy is associated why does depakote cause weight gain an increased risk of neural tube defects NTDs; e. Studies of valproic acid that used bacterial and mammalian test systems have shown no evidence to date of a mutagenic potential for the drug.
craniofacial defects, cardiovascular malformations, malformations involving various body systems In utero exposure to valproic acid also can cause decreased intelligence quotient IQ scores and other adverse cognitive effects in children.
spina bifida and other major congenital malformations e. The importance of these findings to humans is not known. In rats and mice receiving valproic acid dosages of 80 and 170 mg/kg daily for 2 years, an increased incidence of subcutaneous fibrosarcomas occurred in why does depakote cause weight gain rats at the higher dosage level and a dose-related trend for an increased incidence of benign pulmonary adenomas was observed in male mice.Depakote alternatives pills:
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I cannot account for those with Bi-Polar I, but this may apply to you if you have been diagnosed with social anxiety, Bipolar II or a mild form of the disorder. I am working on healthy diet and exercise for the weight. I have gained about 40 pounds but it is a small price to pay for the positive changes, is it ok to take levothyroxine at night. I control why does depakote cause weight gain anxiety with occasional klonopin.
Depakote and weight gain causes ot sure if this will change, or it will be necessary to medicate again. owever, there is now an increase in belligerent behavior, and suspicion.
Patients residing in or receiving treatment in certain states may not be eligible. 67 to stop participation.
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The drug should be used with extreme caution and as single-agent therapy in such children, and the benefits of valproic acid therapy weighed against the risks. Valproic acid is contraindicated in patients with depakote and weight gain causes disease or substantial hepatic dysfunction. Valproic acid also is contraindicated in patients with known mitochondrial disorders caused by POLG depakote and weight gain causes and in children younger than 2 years of age suspected of having a POLG-related disorder.
xperience with oral valproic acid therapy in the management of seizures indicates that children younger than 2 years of age are at an increased risk of developing fatal hepatotoxicity.
|Appropriate treatment of hyperammonemia should be initiated and the patient should be evaluated for urea cycle disorders. f such symptoms are present, plasma ammonia concentrations should be determined, and, if these concentrations are increased, valproic acid therapy should why does depakote cause weight gain discontinued.||Om/nursingcentral/view/Davis-Drug-Guide/51781/all/VALPROATES.|
|I discuss this in more detail in this article: Still, I've seen older patients get better and graduate from hospice; many of them benefit from multi-disciplinary care, depakote and weight gain causes attention to their symptoms, and perhaps even discontinuation of other medical care. That said, it's not at all clear that there's depakote and weight gain causes good evidence base for using lorazepam (brand name Ativan) to treat agitation or restlessness in dementia patients on hospice.||81-489.|
|Why does depakote cause weight gain If at any time a patient begins receiving prescription drug coverage under any such federal, state, or government-funded healthcare program, patient will no longer be able to use the Depakote Savings Card and patient must call OPUS Health at. Copay assistance program is not available to patients receiving prescription reimbursement under any federal, state, or government-funded insurance programs (for example, Medicareincluding Part D, Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law or by the patient s health insurance provider.||Why does depakote cause weight gain Usually, less than 15 to 20% of the dose is eliminated by other oxidative mechanisms. Mitochondrial -oxidation is the other major metabolic pathway, typically accounting for over 40% of the dose.|
If the decision is made to use Depakote and weight gain causes or Depakene, you should use effective birth control contraception Tell your healthcare provider right away if you become pregnant while taking Depakote or Depakene, can depakote cause aggression. All women of childbearing age including girls from the start of puberty should talk to their healthcare provider about using other possible treatments instead of Depakote or Depakene.
Y best to you, Wildcat kdavis; yes listen to Wildcat she nailed it and no it is not because you re getting older the medications you are taking Depakote for sure many gain weight.
When my doctor and I changed my drugs because my diagnosis changed I began losing weight and so far have shed 25lbs with hardly any effort. Of course, I eat healthy and exercise but it was changing the why does depakote cause weight gain that did the trick.
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Why does depakote cause weight gain It is not known whether the risk of neural tube defects or decreased IQ in the offspring of women receiving valproate is reduced by folic acid supplementation.
Evidence suggests that folic acid supplementation prior to conception and during the first trimester of pregnancy decreases the risk for congenital neural tube defects in the general population.
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Because of these changes in valproate clearance, monitoring of valproate and concomitant drug concentrations should why does depakote cause weight gain increased whenever enzyme inducing drugs are introduced or withdrawn. Thus, patients on monotherapy will generally have longer half-lives and higher concentrations than patients receiving polytherapy with antiepilepsy drugs. In contrast, drugs that are inhibitors of cytochrome P450 isozymes, e.
antidepressants, may be expected to have little effect on valproate clearance because cytochrome P450 microsomal mediated oxidation is a relatively minor secondary metabolic pathway compared to glucuronidation and beta-oxidation.
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Supplementary information - Some examples of Schedule IV drugs are: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol Schedule V drugs, substances, or chemicals are defined as drugs with lower potential for abuse than Schedule IV and consist of preparations containing limited quantities of certain narcotics.
Some examples of Schedule II drugs are: Combination products with less than 15 milligrams of hydrocodone per dosage unit Vicodin cocaine, methamphetamine, methadone, hydromorphone Dilaudid meperidine Demerol oxycodone OxyContin fentanyl, Dexedrine, Adderall, and Ritalin Schedule III drugs, substances, or chemicals are defined as drugs with a moderate to low potential for physical and psychological dependence.
Schedule III drugs abuse potential is less than Schedule I and Schedule II drugs but more than Schedule IV. Some examples of Schedule III drugs are: Products containing less than 90 milligrams of codeine per dosage unit Tylenol with codeine ketamine, anabolic steroids, testosterone Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence.
What is the time of effectiveness of depakote?
If this medication is used for seizures, do not stop taking it without consulting your doctor. Your condition may become worse if the drug is suddenly stopped. Your dose may need to be gradually decreased.
Remember to use it at the same time each day to keep the amount of medication in your blood constant.
Can i take zoloft and depakote together?
16 December 2013. Retrieved 14 February 2014. "Depakote 250mg Tablets - Summary of Product Characteristics". Alphapharm Pty Limited.
Does depakote cause rapid eye movement?
Concurrent use of opioids and benzodiazepines has increasingly caused deaths. In Finland, 90% of subjects with opioid dependence are dependent on benzodiazepines too.
What herbs does depakote interact with?
Valproate passes into breast milk, but its effects on developing babies remain unknown. You should tell your healthcare professional right away if you become pregnant while depakote and weight gain causes valproate. You and your healthcare provider should decide if you should continue to take valproate while you are pregnant.
Is depakote dangerous?
Pregnant women taking valproate may develop clotting abnormalities including thrombocytopenia, hypofibrinogenemia, and/or decrease in other coagulation factors, which may result in hemorrhagic complications in the neonate including death see Warnings and Precautions 5. If valproate is used in pregnancy, the clotting parameters should be monitored carefully in the mother.
However, discontinuation of the drug may be considered prior to and during pregnancy in individual cases if depakote and weight gain causes seizure disorder severity and frequency do not pose a serious threat to the patient.
What is normal depakote level?
Children under the age of two years are at a considerably increased risk of why does depakote cause weight gain fatal hepatotoxicity, especially those on multiple anticonvulsants, those with congenital metabolic disorders, those with severe seizure disorders accompanied by mental retardation, and those with organic brain disease.
Serum liver tests should be performed prior to therapy and at frequent intervals thereafter, especially during the first six months see Warnings and Precautions 5.
Is depakote an maoi inhibitor?
High ammonia levels in your blood: feeling tired, vomiting, changes in mental status. Bleeding problems: red or purple spots on your skin, bruising, pain and swelling into your joints due to bleeding or bleeding from your mouth or nose.
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Ask your healthcare provider about the best way to feed your baby. have or think you have a genetic liver problem caused by a mitochondrial disorder e. Alpers Huttenlocher Syndrome are allergic to divalproex sodium, valproic acid, sodium valproate, or any of depakote and weight gain causes ingredients in DEPAKOTE are taking it to prevent migraine headaches and are either pregnant or may become pregnant because you are not using effective birth control contraception have a genetic liver problem caused by a mitochondrial disorder e.
Alpers Huttenlocher Syndrome are pregnant or breastfeeding since DEPAKOTE can pass into breast milk.
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Reviewer specialties include internal medicine, gastroenterology, oncology, orthopedic surgery why does depakote cause weight gain psychiatry. Depakote side effects can be serious and sometimes fatal. People also use it to manage the manic phase of bipolar disorder. The medication Depakote divalproex sodium is an anticonvulsant. oard-certified physicians medically review Drugwatch content to ensure its accuracy why does depakote cause weight gain quality.
Doctors prescribe it to treat seizure disorders and to prevent migraine headaches.
Depakote is one of the standard epilepsy medicines, and many people who take Depakote and the other forms of valproate experience few side effects and enjoy improved control of their seizures. The most common side effects include: elevated blood ammonia levels, suggested by sleepiness, headache, confusion, or nausea Tiredness occurs in many individuals and is often associated with high doses and blood levels.
fewer seizures, a significantly smaller decrease. depakote and weight gain causes
This includes medicines you buy without a prescription, including herbal medicines. Talk to your doctor about how this will affect you. Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines.
Why does depakote cause weight gain Panels: Valproic acid levels are not traditionally included in standard toxicology panels; however, they should be considered on a case-specific basis when evaluating patients with known seizure disorder, patients presenting with altered mental status, and in patients suspected of drug ingestion/overdose A valproic acid level measures the amount of valproic acid in why does depakote cause weight gain blood: either the total level or free level of the drug.
Valproic acid levels should be obtained on patients taking this medication regularly for medical treatment and should also be considered in addition to standard toxicology panels when ingestion or overdose of valproic acid is suspected.
In fact, a large majority of women who use Depakote ER during pregnancy have normal, healthy babies. Depakote ER is listed in Pregnancy Category Why does depakote cause weight gain. This means that there is a risk to the baby, but the benefits may outweigh the risk for some women. Children taking a combination of Depakote and another seizure medicine usually need the higher doses because of interactions between the medicines.
In the United States, the Food and Drug Administration FDA assigns each medication to a Pregnancy Category according to whether it has been proven to be harmful in pregnancy.
Rg/fact-sheets/folic-acid/. Does taking why does depakote cause weight gain acid in pregnancy cause long-term problems in behavior or learning for the baby? Some, but not all, of the women taking valproic acid may have a smaller baby below six pounds at birth There have been reports of temporary low blood sugar levels hypoglycemia and some temporary behavior why does depakote cause weight gain in the newborns.
For more information on folic acid, please see the MotherToBaby fact sheet at: othertobaby. An increased chance for behavior and learning problems has been seen in babies who were exposed to valproic acid during pregnancy. Could taking valproic acid in the second or third trimester cause other pregnancy complications?
Medline. 2000 Dec. 86-93.