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Tadalafil
Clinical data
Pronunciation/ t ə ˈ d æ l ə f ɪ l / tə- DAL -ə-fil
Trade namesCialis, Adcirca, Tadacip, others
AHFS/Drugs.comMonograph
MedlinePlusa604008
License dataEU  EMA:  by INN
Pregnancy categoryB
Routes of administrationBy mouth (tablets)
ATC codeG04BE08 ( WHO )
Legal status
Legal statusIn general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityVaries
Protein binding94%
MetabolismLiver (predominantly CYP3A4)
MetabolitesCatechol metabolite
Elimination half-life17.5 hours
ExcretionFeces (~61%), urine (~36%) [1]

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It may also be used to treat BPH or benign enlargement of the prostate and pulmonary arterial hypertension. The medication is marketed under the name Adcirca and given in higher doses to treat pulmonary hypertension.

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Patients taking either Cialis or Viagra when treating ED typically report of the following side effects common for both drugs: nausea, headache, stomach upset, and flushing.

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As is with every drug Cialis leads to few side effects that are common. The most common effects of this drug are headache, stomach upset, back-ache, muscle- ache, swelling of face, and stuffy or runny nose.

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Cialis sin receta en farmacia tadalafilo no debe utilizarse durante la lactancia. Se observaron efectos en perros que podr an indicar cialis sin receta en farmacia trastorno en la fertilidad. No se puede excluir el riesgo en ni os lactantes. Como medida de precauci n, es preferible evitar el uso de tadalafilo durante el embarazo.

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In ED, pills are generally safe and well cialis sin receta en farmacia. But in many men with erectile dysfunction, this intricate system is out of balance, and sildenafil Viagra vardenafil Levitra or tadalafil Cialis often sets things right. The ED pills all inhibit PDE-5, increasing the supply of cGMP; in about 70% of men cialis sin receta en farmacia ED, the extra cGMP will allow firm and sustainable erections to develop in response to sexual stimulation.

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This selectivity for PDE5 over PDE3 is important because PDE3 is an enzyme involved in cardiac contractility. Additionally, tadalafil is approximately 700-fold more potent for PDE5 than for PDE6, an enzyme which is found in the retina and is responsible for phototransduction.

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