| 14 September 2010

| Date | Team | Time | Result | Rec |
|
APRIL (11-15) |
||||
| 4/1 | @ Rangers | 4:05 pm | L, 9-5, WP: Oliver LP: Bard | 0-1 |
| 4/2 | @ Rangers | 8:05 pm | L, 12-5, WP: Lewis LP: Lackey | 0-2 |
| 4/3 | @ Rangers | 3:05 pm | L, 5-1, WP: Harrison LP: Buchholz | 0-3 |
| 4/5 | @ Indians | 7:05 pm | L, 3-1, WP: Tomlin LP: Beckett SV: C. Perez | 0-4 |
| 4/6 | @ Indians | 7:05 p.m. | L, 8-4, WP: R. Perez LP: Matsuzaka | 0-5 |
| 4/7 | @ Indians | 12:05 pm | L, 1-0, WP: R. Perez LP: Bard SV: C. Perez | 0-6 |
| 4/8 | Yankees | 2:05 pm | W, 9-6, WP: Lackey LP: Colon SV: Papelbon | 1-6 |
| 4/9 | Yankees | 1:10 pm | L, 9-4, WP: Robertson LP: Buchholz | 1-7 |
| 4/10 | Yankees | 8:05 pm | W, 4-0, WP: Beckett LP: Sabathia | 2-7 |
| 4/11 | Rays | 7:10 pm | L, 16-5, WP: Hellickson LP: Matsuzaka | 2-8 |
| 4/12 | Rays | 7:10 pm | L, 3-2, WP: Price LP: Lester SV: Farnsworth | 2-9 |
| 4/13 | Rays | 7:10 pm | PPD | - |
| 4/15 | Blue Jays | 7:10 pm | L, 7-6, WP: Cecil LP: Jenks SV: Rauch | 2-10 |
| 4/16 | Blue Jays | 1:10 pm | W, 4-1, WP: Beckett LP: Reyes SV: Papelbon | 3-10 |
| 4/17 | Blue Jays | 1:35 pm | W, 8-1, WP: Lester LP: Litsch | 4-10 |
| 4/18 | Blue Jays | 11:05 am | W, 9-1, WP: Matsuzaka LP: Romero | 5-10 |
| 4/19 | @ Athletics | 10:05 pm | L, 5-0, WP: Anderson LP: Lackey | 5-11 |
| 4/20 | @ Athletics | 3:35 pm | W, 5-3, WP: Buchholz LP: Gonzalez SV: Papelbon | 6-11 |
| 4/21 | @ Angels | 10:05 pm | W, 4-2, WP: Jenks LP: Thompson SV: Papelbon | 7-11 |
| 4/22 | @ Angels | 10:05 pm | W, 4-3, WP: Lester LP: Haren SV: Papelbon | 8-11 |
| 4/23 | @ Angels | 9:05 pm | W, 5-0, WP: Matsuzaka LP: Santana | 9-11 |
| 4/24 | @ Angels | 3:35 pm | W, 7-0, WP: Lackey LP: Palmer | 10-11 |
| 4/26 | @ Orioles | 7:05 pm | L, 4-1, WP: Britton LP: Buchholz SV: Gregg | 10-12 |
| 4/27 | @ Orioles | 7:05 pm | L, 5-4, WP: Uehara LP: Bard SV: Gregg | 10-13 |
| 4/28 | @ Orioles | 7:05 pm | W, 6-2, WP: Lester LP: Johnson | 11-13 |
| 4/29 | Mariners | 7:10 pm | L, 5-4, WP: Vargas LP: Jenks SV: League | 11-14 |
| 4/30 | Mariners | 7:10 pm | L, 2-0, WP: Fister LP: Lackey SV: League | 11-15 |
|
MAY (19-10) |
||||
| 5/1 | Mariners | 1:35 pm | W, 3-2, WP: Papelbon LP: Wright | 12-15 |
| 5/2 | Angels | 7:10 pm | W, 9-5, WP: Buchholz LP: Weaver | 13-15 |
| 5/3 | Angels | 7:10 pm | W, 7-3, WP: Lester LP: Haren | 14-15 |
| 5/4 | Angels | 7:10 pm | L, 5-3, WP: Bell LP: Matsuzaka | 14-16 |
| 5/5 | Angels | 1:35 pm | L, 11-0, WP: Pineiro LP: Lackey | 14-17 |
| 5/6 | Twins | 7:10 pm | L, 9-2, WP: Baker LP: Wakefield | 14-18 |
| 5/7 | Twins | 1:10 pm | W, 4-0, WP: Buchholz LP: Duensing | 15-18 |
| 5/8 | Twins | 1:35 pm | W, 9-5, WP: Matusuzaka LP: Pavano | 16-18 |
| 5/9 | Twins | 7:10 pm | W, 2-1, WP: Okajima LP: Hoey | 17-18 |
| 5/10 | @ Blue Jays | 7:07 pm | L, 7-6, WP: Villanueva LP: Albers | 17-19 |
| 5/11 | @ Blue Jays | 7:07 pm | L, 9-3, WP: Litsch LP: Lackey | 17-20 |
| 5/13 | @ Yankees | 7:05 pm | W, 5-4, WP: Buchholz LP: Colon SV: Papelbon | 18-20 |
| 5/14 | @ Yankees | 7:10 pm | W, 6-0, WP: Beckett LP: Sabathia | 19-20 |
| 5/15 | @ Yankees | 8:05 pm | W, 7-5, WP: Lester LP: Garcia SV: Papelbon | 20-20 |
| 5/16 | Orioles | 7:10 pm | W, 8-7, WP: Aceves LP: Gregg | 21-20 |
| 5/17 | Orioles | 7:10 pm | PPD | - |
| 5/18 | Tigers | 7:10 pm | W, 1-0, WP: Bard LP: Schlereth SV: Papelbon | 22-20 |
| 5/19 | Tigers | 7:10 pm | W, 4-3, WP: Papelbon LP: Alburquerque | 23-20 |
| 5/20 | Cubs | 7:10 pm | W, 15-5, WP: Lester LP: Davis SV: Atchison | 24-20 |
| 5/21 | Cubs | 7:10 pm | L, 9-3, WP: Marshall LP: Albers | 24-21 |
| 5/22 | Cubs | 8:05 pm | W, 5-1, WP: Wakefield LP: Russell | 25-21 |
| 5/23 | @ Indians | 7:05 pm | L, 3-2, WP: Smith LP: Bard SV: C. Perez | 25-22 |
| 5/24 | @ Indians | 7:05 pm | W, 4-2, WP: Beckett LP: Carmona SV: Papelbon | 26-22 |
| 5/25 | @ Indians | 12:05 pm | W, 14-2, WP: Lester LP: Talbot | 27-22 |
| 5/26 | @ Tigers | 1:05 pm | W, 14-1, WP: Aceves LP: Scherzer | 28-22 |
| 5/27 | @ Tigers | 7:05 pm | W, 6-3, WP: Wakefield LP: Porcello | 29-22 |
| 5/29 | @ Tigers | 1:05 pm | W, 4-3, WP: Albers LP: Valverde SV: Papelbon | 30-22 |
| 5/29 | @ Tigers | 7:05 pm | L, 3-0, WP: Verlander LP: Beckett SV: Valverde | 30-23 |
| 5/30 | White Sox | 7:10 pm | L, 7-3, WP: Peavy LP: Lester |
30-24 |
| 5/31 | White Sox | 7:10 pm | L, 10-7, WP: Humber LP: Aceves SV: Sale |
30-25 |
|
JUNE (16-9) |
||||
| 6/1 | White Sox | 1:35 pm | L, 7-4, WP: Floyd LP: Albers SV: Santos |
30-26 |
| 6/3 | Athletics | 7:10 pm | W, 8-6, WP: Jenks LP: Devine SV: Papelbon |
31-26 |
| 6/4 | Athletics | 1:10 pm | W, 9-8, WP: Aceves LP: Moscoso | 32-26 |
| 6/5 | Athletics | 1:35 pm | W, 6-3, WP: Lackey LP: Anderson SV: Bard |
33-26 |
| 6/7 | @ Yankees | 7:05 pm | W, 6-4, WP: Lester LP: Garcia SV: Papelbon | 34-26 |
| 6/8 | @ Yankees | 7:05 pm | W, 11-6, WP: Wakefield LP: Burnett SV: Aceves |
35-26 |
| 6/9 | @ Yankees | 7:05 pm | W, 8-3, WP: Beckett LP: Sabathia |
36-26 |
| 6/10 | @ Blue Jays | 7:07 pm | W, 5-1, WP: Buchholz LP: Reyes |
37-26 |
| 6/11 | @ Blue Jays | 1:07 pm | W, 16-4, WP: Lackey LP: Morrow | 38-26 |
| 6/12 | @ Blue Jays | 1:07 pm | W, 14-1, WP: Lester LP: Drabek |
39-26 |
| 6/14 | @ Rays | 7:10 pm | L, 4-0, WP: Shields LP: Wakefield |
39-27 |
| 6/15 | @ Rays | 7:10 pm | W, 3-0, WP: Beckett LP: Hellickson |
40-27 |
| 6/16 | @ Rays | 7:10 pm | W, 4-2, WP: Buchholz LP: Price SV: Papelbon | 41-27 |
| 6/17 | Brewers | 7:10 pm | W, 10-4, WP: Lackey LP: Estrada |
42-27 |
| 6/18 | Brewers | 7:10 pm | L, 4-2, WP: Wolf LP: Lester SV: Axford |
42-28 |
| 6/19 | Brewers | 1:35 pm | W, 12-3, WP: Wakefield LP: Gallardo |
43-28 |
| 6/20 | Padres | 7:10 pm | W, 14-5, WP: Albers LP: Luebke |
44-28 |
| 6/21 | Padres | 7:10 pm | L, 5-4, WP: Qualls LP: Wheeler SV: Bell |
44-29 |
| 6/22 | Padres | 1:35 pm | L, 5-1, WP: Richard LP: Lackey |
44-30 |
| 6/24 | @ Pirates | 7:05 pm | L, 3-1, WP: Maholm LP: Lester SV: Hanrahan |
44-31 |
| 6/25 | @ Pirates | 7:05 pm | L, 6-4, WP: Karstens LP: Wakefield: SV: Hanrahan |
44-32 |
| 6/26 | @ Pirates | 1:35 pm | W, 4-2, WP: Miller LP: Wood SV: Papelbon | 45-32 |
| 6/28 | @ Phillies | 7:05 pm | L, 5-0, WP: Lee LP: Beckett |
45-33 |
| 6/29 | @ Phillies | 7:05 pm | L, 2-1, WP: Worley LP: Lackey SV: Bastardo |
45-34 |
| 6/30 | @ Phillies | 1:05 pm | W, 5-2, WP: Lester LP: Herndon SV: Papelbon |
46-34 |
| JULY (20-6) |
||||
| 7/1 | @ Astros | 8:05 pm | W, 7-5, WP: Wheeler LP: Escalona SV: Papelbon |
47-34 |
| 7/2 | @ Astros | 7:05 pm | W, 10-4, WP: Miller LP: Happ |
48-34 |
| 7/3 | @ Astros | 2:05 pm | W, 2-1, WP: Beckett LP: Melancon SV: Papelbon |
49-34 |
| 7/4 | Blue Jays | 1:35 pm | L, 9-7, WP: Morrow LP: Lackey SV: Francisco |
49-35 |
| 7/5 | Blue Jays | 7:10 pm | W, 3-2, WP: Albers LP: Cecil SV: Papelbon |
50-35 |
| 7/6 | Blue Jays | 7:10 pm | W, 6-4, WP: Wakefield LP: Romero SV: Papelbon |
51-35 |
| 7/7 | Orioles | 7:10 pm | W, 10-4, WP: Miller LP: Arrieta |
52-35 |
| 7/8 | Orioles | 7:10 pm | W, 10-3, WP: Beckett LP: Britton |
53-35 |
| 7/9 | Orioles | 7:10 pm | W, 4-0, WP: Lackey LP: Simon |
54-35 |
| 7/10 | Orioles | 1:35 pm | W, 8-6, WP: Aceves LP: Guthrie SV: Papelbon |
55-35 |
| 7/15 | @ Rays | 7:10 pm | L, 9-6, WP: Price LP: Miller SV: Farnsworth |
55-36 |
| 7/16 | @ Rays | 4:10 pm | W, 9-5, WP: Lackey LP: Shields |
56-36 |
| 7/17 | @ Rays | 8:05 pm | W, 1-0, WP: Aceves LP: Russell SV: Papelbon |
57-36 |
| 7/18 | @ Orioles | 7:05 pm | W, 15-10, WP: Wheeler LP: Gonzalez | 58-36 |
| 7/19 | @ Orioles | 7:05 pm | L, 6-2, WP: Guthrie LP: Weiland SV: Johnson |
58-37 |
| 7/20 | @ Orioles | 12:35 pm | W, 4-0, WP: Miller LP: Arrieta |
59-37 |
| 7/22 | Mariners | 7:10 pm | W, 7-4, WP: Lackey LP: Hernandez SV: Papelbon |
60-37 |
| 7/23 | Mariners | 7:10 pm | W, 3-1, WP: Beckett LP: Beavan SV: Papelbon |
61-37 |
| 7/24 | Mariners | 1:35 pm | W, 12-8, WP: Wakefield LP: Pineda |
62-37 |
| 7/25 | Royals | 7:10 pm | L, 3-1, WP: Coleman LP: Williams SV: Soria |
62-38 |
| 7/26 | Royals | 7:10 pm | W, 13-9, WP: Aceves LP: Adcock |
63-38 |
| 7/27 | Royals | 7:10 pm | W, 12-5, WP: Lackey LP: Chen | 64-38 |
| 7/28 | Royals | 1:35 pm | L, 4-3, WP: Hochevar LP: Beckett SV: Soria |
64-39 |
| 7/29 | @ White Sox | 8:10 pm | L, 3-1, WP: Floyd LP: Wakefield SV: Santos |
64-40 |
| 7/30 | @ White Sox | 7:10 pm | W, 10-2, WP: Lester LP: Humber | 65-40 |
| 7/31 | @ White Sox | 2:10 pm | W, 5-3, WP: Aceves LP: Crain SV: Papelbon |
66-40 |
| AUGUST (17-11) |
||||
| 8/1 | Indians | 7:10 pm | L, 9-6, WP: R. Perez LP: Bard |
66-41 |
| 8/2 | Indians | 7:10 pm | W, 3-2, WP: Papelbon LP: Pestano |
67-41 |
| 8/3 | Indians | 7:10 pm | W, 4-3, WP: Papelbon LP: J. Smith |
68-41 |
| 8/4 | Indians | 7:10 pm | L, 7-3, WP: Masterson LP: Morales |
68-42 |
| 8/5 | Yankees | 7:10 pm | L, 3-2, WP: Logan LP: Lester SV: Rivera |
68-43 |
| 8/6 | Yankees | 4:10 pm | W, 10-4, WP: Lackey LP: Sabathia |
69-43 |
| 8/7 | Yankees | 8:05 pm |
W, 3-2, WP: Bard LP: Hughes |
70-43 |
| 8/8 | @ Twins | 8:10 pm | W, 8-6, WP: Aceves LP: Perkins SV: Papelbon |
71-43 |
| 8/9 | @ Twins | 8:10 pm | W, 4-3, WP: Albers LP: Capps SV: Papelbon |
72-43 |
| 8/10 | @ Twins | 8:10 pm | L, 5-2, WP: Perkins LP: Lester SV: Nathan |
72-44 |
| 8/12 | @ Mariners | 10:10 pm | W, 6-4, WP: Lackey LP: Beavan SV: Papelbon |
73-44 |
| 8/13 | @ Mariners | 10:10 pm | L, 5-4, WP: Hernandez LP: Beckett SV: League |
73-45 |
| 8/14 | @ Mariners | 4:10 pm | L, 5-3, WP: Furbush LP: Wakefield SV: League |
73-46 |
| 8/16 | Rays | 1:05 p.m | W, 3-1, WP: Lester LP: Shields SV: Papelbon |
74-46 |
| 8/16 | Rays | 7:10 pm | L, 6-2, WP: Niemann LP: Bedard |
74-47 |
| 8/17 | Rays | 1:35 pm | L, 4-0, WP: Price LP: Lackey |
74-48 |
| 8/18 | @ Royals | 8:10 pm | W, 4-3, WP: Beckett LP: Hochevar SV: Papelbon |
75-48 |
| 8/19 | @ Royals | 8:10 pm | W, 7-1, WP: Miller LP: Francis SV: Aceves |
76-48 |
| 8/20 | @ Royals | 7:10 pm | L, 9-4, WP: Paulino LP: Albers | 76-49 |
| 8/21 | @ Royals | 2:10 pm | W, 6-1, WP: Lester LP: Duffy |
77-49 |
| 8/22 | @ Rangers | 8:05 pm | L, 4-0, WP: Wilson LP: Bedard | 77-50 |
| 8/23 | @ Rangers | 8:05 pm | W, 11-5, WP: Lackey LP: Lewis |
78-50 |
| 8/24 | @ Rangers | 7:05 pm | W, 13-2, WP: Beckett LP: Harrison |
79-50 |
| 8/25 | @ Rangers | 8:05 pm | W, 6-0, WP: Miller LP: Ogando |
80-50 |
| 8/26 | Athletics | 7:10 pm | L, 15-5, WP: Gonzalez LP: Wakefield |
80-51 |
| 8/27 | Athletics | 12:00 pm | W, 9-3, WP: Lester LP: Moscoso |
81-51 |
| 8/27 | Athletics | 5:00 pm | W, 4-0, WP: Aceves LP: Godfrey |
82-51 |
| 8/30 | Yankees | 7:10 pm | L, 5-2, WP: Sabathia LP: Lackey SV: Rivera | 82-52 |
| 8/31 | Yankees | 7:10 pm | W, 9-5, WP: Beckett LP: Hughes |
83-52 |
|
SEPTEMBER (7-20) |
||||
| 9/1 | Yankees | 7:10 pm | L, 4-2, WP: Wade LP: Aceves SV: Rivera |
83-53 |
| 9/2 | Rangers | 7:10 pm | L, 10-0, WP: Holland LP: Miller |
83-54 |
| 9/3 | Rangers | 7:10 pm | W, 12-7, WP: Bedard LP: Lewis |
84-54 |
| 9/4 | Rangers | 1:35 pm | L, 11-4, WP: Harrison LP: Lackey |
84-55 |
| 9/5 | @ Blue Jays | 1:07 pm | L, 1-0, WP: Camp LP: Wheeler |
84-56 |
| 9/6 | @ Blue Jays | 7:07 pm | W, 14-0, WP: Lester LP: Perez |
85-56 |
| 9/7 | @ Blue Jays | 7:07 pm | L, 11-10, WP: Camp LP: Bard SV: Francisco |
85-57 |
| 9/8 | @ Blue Jays | 7:07 pm | L, 7-4, WP: Romero LP: Miller |
85-58 |
| 9/9 | @Rays |
7:10 pm | L, 7-2, WP: Davis LP: Lackey |
85-59 |
| 9/10 | @ Rays | 7:10 pm | L, 6-5, WP: Gomes LP: Bard |
85-60 |
| 9/11 | @ Rays | 1:35 pm | L, 9-1, WP: Shields LP: Lester |
85-61 |
| 9/13 | Blue Jays | 7:10 pm | W, 18-6, WP: Wakefield LP: Morrow | 86-61 |
| 9/14 | Blue Jays | 1:35 pm | L, 5-4, WP: Romero LP: Bard SV: Francisco |
86-62 |
| 9/15 | Rays | 7:10 pm | L, 9-2, WP: Hellickson LP: Weiland |
86-63 |
| 9/16 | Rays | 7:10 pm | W, 4-3, WP: Beckett LP: Shields SV: Papelbon |
87-63 |
| 9/17 | Rays | 4:10 pm | L, 4-3, WP: Niemann LP: Lester SV: Peralta |
87-64 |
| 9/18 | Rays | 1:35 pm | L, 8-5, WP: McGee LP: Wakefield SV: Peralta |
87-65 |
| 9/19 | Orioles | 1:05 pm | L, 6-5, WP: Guthrie LP: Weiland SV: Johnson |
87-66 |
| 9/19 | Orioles | 7:10 pm | W, 18-9, WP: Atchison LP: Matusz |
88-66 |
| 9/20 | Orioles | 7:10 pm | L, 7-5, WP: Eyre LP: Bard SV: Johnson |
88-67 |
| 9/21 | Orioles | 7:10 pm | L, 6-4, WP: Rapada LP: Beckett: SV: Johnson |
88-68 |
| 9/24 | @ Yankees | 4:10 pm | L, 9-1, WP: Garcia LP: Lester |
88-69 |
| 9/25 | @ Yankees | 1:05 pm |
L, 6-2, WP: Burnett LP: Wakefield |
88-70 |
| 9/25 | @ Yankees | 6:30 pm | W, 7-4, WP: Morales LP: Proctor SV: Doubront |
89-70 |
| 9/26 | @ Orioles | 7:05 pm | L, 6-3, WP: Patton LP: Beckett | 89-71 |
| 9/27 | @ Orioles | 7:05 pm | W, 8-7, WP: Aceves LP: Britton SV: Papelbon |
90-71 |
| 9/28 | @ Orioles | 7:05 pm | L, 4-3, WP: Johnson LP: Papelbon |
90-72 |
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